D-lor 5mg Tab.
Manufactured By
Npl
Facts
Desloratadine
Action Indications Contraindications Route/Dosage Interactions Lab Test Interferences Adverse Reactions Precautions Patient Care Considerations Administration/Storage Assessment/Interventions Patient/Family Education
(dess-lore-AT-ah-deen) Clarinex Tablets 5 mg Class: Antihistamine
Action Long-acting histamine antagonist with selective H1-receptor histamine antagonist activity.
Indications Relief of nasal and non-nasal symptoms of seasonal and perennial allergic rhinitis; in chronic idiopathic urticaria for relief of symptoms of pruritus and reduction in number and size of hives.
Contraindications Standard considerations.
Route/Dosage
Adults and Children Older Than 12 Yr: PO 5 mg once daily. In patients with renal or hepatic impairment, start with 5 mg qod.
Interactions None well documented.
Lab Test Interferences None well documented.
Adverse Reactions CARDIOVASCULAR: Tachycardia. CNS: Somnolence; fatigue; dizziness. EENT: Pharyngitis; dry throat. GI: Dry mouth; nausea. HEPATIC: Elevated liver enzymes and bilirubin. OTHER: Flu-like symptoms; myalgia; hypersensitivity.
Precautions
Pregnancy: Category C. Lactation: Excreted in breast milk. Children: Safety and efficacy not established in children less than 12 yr. Elderly: Select dose with caution, reflecting greater frequency of decreased hepatic, renal, or cardiac function and comorbidity. Renal or Hepatic Impairment: Dosage adjustment is recommended.
PATIENT CARE CONSIDERATIONS
Administration/Storage
Give once daily without regard to food.
Start patients with kidney or liver impairment on 1 tablet qod.
Store tablets at controlled room temperature. Keep container tightly closed. Protect unit-dose hospital pack from moisture.
Assessment/Interventions
Obtain patient history, including drug history and any known allergies. Note history of hepatic or renal dysfunction.
Assess for allergy symptoms (eg, rhinitis, nasal congestion, sneezing, itching, watery eyes) before and periodically throughout therapy.
Monitor patient for dizziness and excessive drowsiness. If noted, hold therapy and notify health care provider.
OVERDOSAGE: SIGNS & SYMPTOMS Increased heart rate and corrected QT interval
Patient/Family Education
Explain name, dose, action, and potential side effects of drug.
Advise patient to take once daily without regard to meals.
Advise patient that if allergy symptoms are not controlled, not to increase the dose of medication or frequency of use but to inform the health care provider. Inform patient that larger or more frequent dosing does not increase effectiveness and may cause drowsiness.
Caution patient not to take any otc antihistamines while taking this medication unless advised to do so by the health care provider.
If patient is to have allergy skin testing, advise to not take the medication for 6 days or more before the skin testing.
Advise patient to notify health care provider if becoming pregnant, planning on becoming pregnant, or breastfeeding.
Instruct patient to stop taking drug and immediately report any of the following symptoms to health care provider: dizziness, excessive drowsiness.
Caution patient to not take any prescription or otc medications, or dietary supplements unless advised by health care provider.
Books@Ovid
Copyright © 2003 Facts and Comparisons
David S. Tatro
A to Z Drug Facts